The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2019
Filed:
Feb. 12, 2014
Accurna, Inc., Bunkyo-ku, JP;
Kazunori Kataoka, Tokyo, JP;
Keiji Itaka, Tokyo, JP;
Takehiko Ishii, Tokyo, JP;
Hirokuni Uchida, Tokyo, JP;
Satoshi Uchida, Tokyo, JP;
Miyuki Baba, Tokyo, JP;
AccuRna, Inc., Bunkyo-ku, JP;
Abstract
A polyion complex of mRNA and a polycationic polymer, and a composition and a pharmaceutical composition for mRNA delivery are provided. The polyion complex of mRNA and the polycationic polymer can deliver mRNA into cells in the body of a subject almost without inducing inflammation. The polyion complex can then cause mRNA to be uniformly expressed in cells in the body of the subject. The pharmaceutical composition containing the polyion complex is suitable for use in treating a disease whose condition rapidly progresses or an acute disease.