The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2019
Filed:
Jun. 29, 2017
Applicant:
Oncomed Pharmaceuticals, Inc., Redwood City, CA (US);
Inventor:
Austin L Gurney, San Francisco, CA (US);
Assignee:
ONCOMED PHARMACEUTICALS, INC., Redwood City, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/19 (2006.01); C12Q 1/68 (2018.01); C07K 14/00 (2006.01); C07K 14/52 (2006.01); C07K 16/18 (2006.01); C12N 15/00 (2006.01); C12N 15/62 (2006.01); C07K 14/525 (2006.01); C07K 14/715 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01); A61K 39/295 (2006.01);
U.S. Cl.
CPC ...
A61K 38/19 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); C07K 14/00 (2013.01); C07K 14/52 (2013.01); C07K 14/525 (2013.01); C07K 14/7151 (2013.01); C07K 16/18 (2013.01); C12N 15/00 (2013.01); C12N 15/62 (2013.01); C12Q 1/68 (2013.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01); C07K 2317/55 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2319/30 (2013.01);
Abstract
Polypeptides and agents that bind a TNF receptor superfamily protein are disclosed, particularly agents that specifically bind GITR, OX40, or CD40. The polypeptides or agents may include fusion polypeptides, particularly polypeptides comprising GITRL, OX40L, or CD40L and/or bispecific agents. Also disclosed are methods of using the polypeptides or agents for inducing and/or enhancing the immune response, as well as methods for the treatment of diseases such as cancer.