The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2019

Filed:

Aug. 13, 2015
Applicant:

Korea Research Institute of Bioscience and Biotechnology, Daejeon, KR;

Inventors:

Sang Chul Lee, Daejeon, KR;

Baek Soo Han, Daejeon, KR;

Kwang-Hee Bae, Daejeon, KR;

Hyejin Kim, Daejeon, KR;

Won Kon Kim, Daejeon, KR;

Kyoung Jin Oh, Daejeon, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/30 (2015.01); C12N 5/0793 (2010.01); C12N 5/10 (2006.01); A61K 38/17 (2006.01); C12N 5/074 (2010.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/30 (2013.01); A61K 38/1787 (2013.01); C12N 5/0607 (2013.01); C12N 5/0619 (2013.01); C12N 5/10 (2013.01); A61K 45/00 (2013.01); A61K 48/00 (2013.01); C12N 5/00 (2013.01); C12N 2502/08 (2013.01);
Abstract

The present invention relates to a method for producing cholinergic neurons comprising obtaining neural progenitor cells from stem cells so as to continuously produce cholinergic neural cells with high purity and the same traits, followed by differentiating the neural progenitor cells into the cholinergic neurons, and cholinergic neurons produced therefrom. Since the method of preparing the cholinergic neurons provided in the present invention enables not only production of the cholinergic neurons with high purity, but also rapid production of the cholinergic neurons with the same traits, it can be widely used for effectively treating degenerative cranial nerve diseases such as Alzheimer's disease.


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