The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2019

Filed:

Apr. 23, 2015
Applicant:

Hexima Limited, Victoria, AU;

Inventors:
Assignee:

Hexima Limited, La Trobe University, Victoria, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61K 38/17 (2006.01); A01N 37/46 (2006.01); A01N 63/02 (2006.01); A01N 65/38 (2009.01); C07K 14/415 (2006.01); C12N 15/82 (2006.01); A61K 38/01 (2006.01); A61K 8/42 (2006.01); A61Q 5/02 (2006.01); A61Q 17/00 (2006.01); A61Q 19/10 (2006.01); A61K 36/00 (2006.01);
U.S. Cl.
CPC ...
A01N 37/46 (2013.01); A01N 63/02 (2013.01); A01N 65/38 (2013.01); A61K 8/42 (2013.01); A61K 38/011 (2013.01); A61K 38/16 (2013.01); A61K 38/1729 (2013.01); A61Q 5/02 (2013.01); A61Q 17/005 (2013.01); A61Q 19/10 (2013.01); C07K 14/415 (2013.01); C12N 15/8279 (2013.01); C12N 15/8282 (2013.01); A61K 36/00 (2013.01);
Abstract

Agents and natural and synthetic formulations and extracts are useful in control of pathogen infection and infestation in humans, animals and plants, as well as pathogen contamination in environmental locales. A method inhibits growth or infection or infestation of a pathogen, including contacting the pathogen with an effective amount of a combination of a plant defensin or a functional natural or synthetic derivative or variant thereof and a non-defensin peptide, such as a cathelicidin peptide, a hairpin peptide, a hairpin peptide from which disulfide bridges have been removed, indolicidin, synthetic peptide CP-29, or a peptide derived from a cystatin. The combination of the defensin and peptide are synergistic compared to the use of each alone at the same individual dose as used in the combination.


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