The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2019
Filed:
Jul. 12, 2017
Emulate Inc., Boston, MA (US);
Janssen Biotech, Inc, Horsham, PA (US);
Daniel Levner, Brookline, MA (US);
Christopher David Hinojosa, Cambridge, MA (US);
Norman Wen, West Roxbury, MA (US);
Jacob Fraser, Somerville, MA (US);
Justin Nguyen, Medford, MA (US);
Riccardo Barrile, Boston, MA (US);
Geraldine Hamilton, Boston, MA (US);
Catherine Karalis, Brookline, MA (US);
Hyoungshin Park, Newton, MA (US);
Antonio Varone, West Roxbury, MA (US);
Andries Van der Meer, Enchede, NL;
Monicah Otieno, Robbinville, NJ (US);
David Conegliano, Boston, MA (US);
EMULATE, Inc., Boston, MA (US);
Abstract
Compositions, devices and methods are described for preventing, reducing, controlling or delaying adhesion, adsorption, surface-mediated clot formation, or coagulation in a microfluidic device or chip. In one embodiment, blood (or other fluid with blood components) that contains anticoagulant is introduced into a microfluidic device comprising one or more additive channels containing one or more reagents that will re-activate the native coagulation cascade in the blood that makes contact with it 'on-chip' before moving into the experimental region of the chip.