The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2019
Filed:
Jan. 25, 2013
Applicant:
Deutsches Krebsforschungszentrum, Heidelberg, DE;
Inventors:
Antonio Marchini, Heidelberg, DE;
Jean Rommelaere, Heidelberg, DE;
Barbara Leuchs, Heidelberg, DE;
Anna Illarionova, Heidelberg, DE;
Assignee:
DEUTSCHES KREBSFORSCHUNGSZENTRUM, Heidelberg, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/86 (2006.01); C12N 15/11 (2006.01); A01K 67/027 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A01K 67/0275 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01); C12N 2320/32 (2013.01); C12N 2330/51 (2013.01); C12N 2750/14343 (2013.01);
Abstract
Described are methods for efficiently down regulating the expression of a gene of interest in a cell by use of a modified rodent parvovirus that contains an expressible target specific nucleic acid, preferably an shRNA expression cassette. Also described are cells or organisms comprising said parvovirus.