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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10227593 B1

PDFFull Text
Date of Patent:
Mar. 12, 2019

Filed:

Dec. 23, 2016

Methods, systems, and compositions for cell-derived/vesicle-based microrna delivery

Applicant:

Henry Ford Health System, Detroit, MI (US);

Inventors:

Mark E. Katakowski, Ann Arbor, MI (US);

Benjamin A. L. Buller, Detroit, MI (US);

Michael Chopp, Southfield, MI (US);

Assignee:

Henry Ford Health System, Detroit, MI (US);

Attorneys:

Cooley LLP

Ivor R. Elrifi

Matthew Pavao

Primary Examiner:

Amy H Bowman

Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61K 35/28 (2015.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); A61K 35/12 (2013.01); A61K 35/28 (2013.01); C12N 15/113 (2013.01); C12N 2310/141 (2013.01); C12N 2320/32 (2013.01);
Abstract

Some embodiments comprise methods, systems, and compositions to produce and/or administer modified exosomes or other vesicles containing one or more selected microRNAs, including but not limited to, miR-146b. Some embodiments also comprise the therapeutic administration and use of such modified exosomes and/or producer cells to treat mammalian brain or neurologic injuries and diseases, including in human beings.

Find Patent Forward Citations

Katakowski, Mark. (2019). Methods, systems, and compositions for cell-derived/vesicle-based microrna delivery (U.S. Patent No. 10227593). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10227593

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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