The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10227589 B1

PDF
Full Text
Expired
Date of Patent:
Mar. 12, 2019

Filed:

Jan. 28, 2013
Applicant:

Council of Scientific and Industrial Research, New Delhi, IN;

Inventors:

Anubhab Mukherjee, Andhra Pradesh, IN;

Jayanta Bhattacharyya, Andhra Pradesh, IN;

Arabinda Chaudhuri, Andhra Pradesh, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 15/111 (2013.01); C12N 15/1135 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01); C12N 2320/32 (2013.01);
Abstract

Liposomal compositions comprising of liposomes of guanidinylated cationic amphiphiles as the main lipid and cholesterol/1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC)/aminopropyl polyethyleneglycol carbamyl-distearoylphosphatidyl-ethanolamine (DSPE-peg-NH) as co-lipids are described. These liposomal compositions containing encapsulated or electrostatically complexed therapeutic small interfering RNAs (siRNAs) against Cdc20, a key cell cycle regulator, inhibit solid tumor growth and melanoma tumor growth on lung in C57BL/6J mice.


Find Patent Forward Citations

Mukherjee, Anubhab. (2019). Method for inhibiting tumor growth through rna-interference using liposomally associated cdc20 sirna (U.S. Patent No. 10227589). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10227589

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