The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 12, 2019

Filed:

Oct. 01, 2014
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Jeremy Lee Baryza, Cambridge, MA (US);

Marcel Blommers, Basel, CH;

Cesar Fernandez, Basel, CH;

Erin Geno, Cambridge, MA (US);

Alvar Gossert, Basel, CH;

Paulette Greenidge, Basel, CH;

Dieter Huesken, Basel, CH;

Juerg Hunziker, Basel, CH;

Francois Jean-Charles Natt, Basel, CH;

Anup Patnaik, Cambridge, MA (US);

Andrew Patterson, Cambridge, MA (US);

Jean-Michel Rene Rondeau, Basel, CH;

Jan Weiler, Cambridge, MA (US);

Meicheng Zhu, Cambridge, MA (US);

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/11 (2006.01); C07D 215/12 (2006.01); C07D 215/14 (2006.01); C07D 311/80 (2006.01); C07C 69/40 (2006.01); C07D 217/14 (2006.01); C07D 401/04 (2006.01); C07D 213/30 (2006.01); C07C 43/23 (2006.01); C07C 233/01 (2006.01); C07D 217/16 (2006.01); C07D 217/18 (2006.01);
U.S. Cl.
CPC ...
C12N 15/111 (2013.01); C07C 43/23 (2013.01); C07C 69/40 (2013.01); C07C 233/01 (2013.01); C07D 213/30 (2013.01); C07D 215/12 (2013.01); C07D 215/14 (2013.01); C07D 217/14 (2013.01); C07D 217/16 (2013.01); C07D 217/18 (2013.01); C07D 311/80 (2013.01); C07D 401/04 (2013.01); C12N 2310/14 (2013.01); C12N 2310/344 (2013.01); C12N 2310/351 (2013.01); C12N 2320/51 (2013.01);
Abstract

The disclosure relates to novel compounds and compositions comprising a RNAi agent comprising a novel compound as a 3' end cap. The disclosure also relates to processes for making such compositions, and methods and uses of such compositions, e.g., to mediate RNA interference.


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