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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10227588 B1

PDFFull Text
Date of Patent:
Mar. 12, 2019

Filed:

Oct. 01, 2014

3'end caps for rnai agents for use in rna interference

Applicant:

Novartis Ag, Basel, CH;

Inventors:

Jeremy Lee Baryza, Cambridge, MA (US);

Marcel Blommers, Basel, CH;

Cesar Fernandez, Basel, CH;

Erin Geno, Cambridge, MA (US);

Alvar Gossert, Basel, CH;

Paulette Greenidge, Basel, CH;

Dieter Huesken, Basel, CH;

Juerg Hunziker, Basel, CH;

Francois Jean-Charles Natt, Basel, CH;

Anup Patnaik, Cambridge, MA (US);

Andrew Patterson, Cambridge, MA (US);

Jean-Michel Rene Rondeau, Basel, CH;

Jan Weiler, Cambridge, MA (US);

Meicheng Zhu, Cambridge, MA (US);

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:

Brinks Gilson & Lione

Primary Examiner:

Kimberly Chong

Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/11 (2006.01); C07D 215/12 (2006.01); C07D 215/14 (2006.01); C07D 311/80 (2006.01); C07C 69/40 (2006.01); C07D 217/14 (2006.01); C07D 401/04 (2006.01); C07D 213/30 (2006.01); C07C 43/23 (2006.01); C07C 233/01 (2006.01); C07D 217/16 (2006.01); C07D 217/18 (2006.01);
U.S. Cl.
CPC ...
C12N 15/111 (2013.01); C07C 43/23 (2013.01); C07C 69/40 (2013.01); C07C 233/01 (2013.01); C07D 213/30 (2013.01); C07D 215/12 (2013.01); C07D 215/14 (2013.01); C07D 217/14 (2013.01); C07D 217/16 (2013.01); C07D 217/18 (2013.01); C07D 311/80 (2013.01); C07D 401/04 (2013.01); C12N 2310/14 (2013.01); C12N 2310/344 (2013.01); C12N 2310/351 (2013.01); C12N 2320/51 (2013.01);
Abstract

The disclosure relates to novel compounds and compositions comprising a RNAi agent comprising a novel compound as a 3' end cap. The disclosure also relates to processes for making such compositions, and methods and uses of such compositions, e.g., to mediate RNA interference.

Find Patent Forward Citations

Baryza, Jeremy. (2019). 3'end caps for rnai agents for use in rna interference (U.S. Patent No. 10227588). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10227588

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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