The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 12, 2019

Filed:

Sep. 06, 2016
Applicant:

Wayne State University, Detroit, MI (US);

Inventors:

Bonnie F. Sloane, Royal Oak, MI (US);

Yong Xu, Troy, MI (US);

Kyungmin Ji, Troy, MI (US);

Hongen Tu, Warren, MI (US);

Kamiar Moin, West Bloomfield, MI (US);

Kingsley Osuala, Detroit, MI (US);

Assignee:

Wayne State University, Detroit, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); C12M 3/00 (2006.01); C12M 1/34 (2006.01); G01N 33/50 (2006.01); C12M 1/12 (2006.01); C12N 5/00 (2006.01); C12N 5/09 (2010.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C12M 41/46 (2013.01); C12M 23/22 (2013.01); C12M 23/26 (2013.01); C12M 23/34 (2013.01); C12M 23/38 (2013.01); C12M 23/58 (2013.01); C12M 25/14 (2013.01); C12M 29/26 (2013.01); C12M 41/12 (2013.01); C12M 41/26 (2013.01); C12M 41/34 (2013.01); C12N 5/0062 (2013.01); C12N 5/0656 (2013.01); C12N 5/0693 (2013.01); G01N 33/5008 (2013.01); C12N 2500/02 (2013.01); C12N 2500/32 (2013.01); C12N 2500/84 (2013.01); C12N 2501/999 (2013.01); C12N 2502/1323 (2013.01); C12N 2502/30 (2013.01); C12N 2509/00 (2013.01);
Abstract

Cell culture devices and methods of their use are provided according to aspects of the present invention which include a base having a pair of spaced apart wells and at least one fluid port defined from an exterior of the base to each of the wells, each fluid port being spaced above the base sheet by a distance sufficient to introduce a material above a matrix deposited on the base sheet in the wells; and a cover having a pair of spaced apart well covering portions that are each disposed above a respective one of the one spaced apart wells of the base body when the cover is covering the upper surface of the base body and having a gas passage defined between the spaced apart well covering portions and at least one gas port defined from an exterior of the cover to each of the well covering portions.


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