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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10227382 B1

PDFFull Text
Date of Patent:
Mar. 12, 2019

Filed:

Mar. 30, 2017

Method of designing a peptide and/or peptide derivative for modulating gamma-c-cytokine activity

Applicant:

Bioniz, Llc, Irvine, CA (US);

Inventors:

Yutaka Tagaya, Rockville, MD (US);

Nazli Azimi, San Juan Capistrano, CA (US);

Assignee:

BIONIZ, LLC, Irvine, CA (US);

Attorney:

Knobbe, Martens, Olson & Bear, LLP

Primary Examiner:

Julie Ha

Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/10 (2006.01); A61K 38/20 (2006.01); A61K 8/64 (2006.01); C07K 7/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/52 (2006.01); C07K 14/54 (2006.01); A61Q 3/00 (2006.01); A61Q 7/00 (2006.01); A61Q 19/00 (2006.01); A61Q 19/08 (2006.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 8/64 (2013.01); A61K 38/20 (2013.01); A61K 47/642 (2017.08); A61K 47/643 (2017.08); A61Q 3/00 (2013.01); A61Q 7/00 (2013.01); A61Q 19/00 (2013.01); A61Q 19/004 (2013.01); A61Q 19/08 (2013.01); C07K 7/06 (2013.01); C07K 14/52 (2013.01); C07K 14/54 (2013.01); A61K 38/00 (2013.01); A61K 38/10 (2013.01);
Abstract

The γc-family cytokines, Interleukin-2 (IL-2), Interleukin-4 (IL-4), Interleukin-7 (IL-7), Interleukin-9 (IL-9), Interleukin-15 (IL-15), and Interleukin-21 (IL-21), are associated with important human diseases, such as leukemia, autoimmune diseases, collagen diseases, diabetes mellitus, skin diseases, degenerative neuronal diseases and graft-versus-host disease (GvHD). Thus, inhibitors of γc-cytokine activity are valuable therapeutic and cosmetic agents as well as research tools. Peptide and/or peptide derivative antagonists based on the consensus γc-subunit binding site to inhibit γc-cytokine activity are described. Also described are peptide and/or peptide derivative antagonists exhibiting Simul-Block activity, and inhibiting the activity of multiple γc-cytokine family members.

Find Patent Forward Citations

Tagaya, Yutaka. (2019). Method of designing a peptide and/or peptide derivative for modulating gamma-c-cytokine activity (U.S. Patent No. 10227382). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10227382

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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