The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 12, 2019

Filed:

Sep. 05, 2013
Applicant:

Plexxikon Inc., Berkeley, CA (US);

Inventors:

Jack Lin, Hercules, CA (US);

John Buell, San Francisco, CA (US);

Katrina Chan, Fremont, CA (US);

Todd Ewing, Walnut Creek, CA (US);

Prabha Ibrahim, Mountain View, CA (US);

Marika Nespi, Berkeley, CA (US);

Phuongly Pham, San Francisco, CA (US);

Songyuan Shi, Fremont, CA (US);

Wayne Spevak, Berkeley, CA (US);

Guoxian Wu, Foster City, CA (US);

Jiazhong Zhang, Burlingame, CA (US);

Ying Zhang, Fremont, CA (US);

Assignee:

Plexxikon Inc., Berkeley, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61K 31/519 (2006.01); C07D 401/12 (2006.01); A61K 31/52 (2006.01); C07D 239/74 (2006.01); A61K 31/5377 (2006.01); C07D 491/056 (2006.01); C07D 473/00 (2006.01); C07D 487/04 (2006.01); A61K 31/517 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/52 (2013.01); A61K 31/5377 (2013.01); C07D 239/74 (2013.01); C07D 401/12 (2013.01); C07D 473/00 (2013.01); C07D 487/04 (2013.01); C07D 491/056 (2013.01); C07D 519/00 (2013.01);
Abstract

Compounds active on c-kit protein kinases or mutant c-kit protein kinases having any mutations are described, as well as methods of making and using such compounds to treat diseases and conditions associated with aberrant activity of the c-kit protein kinases and mutant c-kit protein kinases.


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