The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 12, 2019

Filed:

Apr. 12, 2016
Applicant:

Guizhou Bailing Group Pharmaceutical Co., Ltd., Anshun, Guizhou, CN;

Inventors:

Lijuan Chen, Sichuan, CN;

Yuquan Wei, Sichuan, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 473/34 (2006.01); A61K 31/52 (2006.01); A61K 31/5377 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 473/34 (2013.01); A61K 31/52 (2013.01); A61K 31/5377 (2013.01); A61P 35/00 (2018.01); Y02A 50/411 (2018.01);
Abstract

The present invention relates to the field of the chemical medicines, and in particular, to purinyl-N-hydroxyl pyrimidine formamide derivatives, a preparation method therefor and a use thereof. The present invention provides a purinyl-N-hydroxyl pyrimidine formamide derivative having a structure represented by formula (I). The invention also provides a method for preparing said purinyl-N-hydroxyl pyrimidine formamide derivative and a use thereof. Purinyl-N-hydroxyl pyrimidine formamide derivative provided in the invention can be not only a PI3K and HDAC double-functional target kinase inhibitor, but also a PI3K or HDAC single target kinase inhibitor, thus providing new choice for preparing multi-target inhibitors.


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