The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 12, 2019

Filed:

Sep. 19, 2014
Applicant:

Biomarin Pharmaceutical Inc., Novato, CA (US);

Inventors:

Bing Wang, San Jose, CA (US);

Daniel Chu, Santa Clara, CA (US);

Alexander James Bridges, Saline, MI (US);

Assignee:

BIOMARIN PHARMACEUTICAL INC., Novato, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/12 (2006.01); C07D 471/04 (2006.01); C07D 491/056 (2006.01); C07D 211/46 (2006.01); C07D 205/02 (2006.01); C07D 231/56 (2006.01); C07D 215/06 (2006.01); C07D 319/18 (2006.01); C07D 405/14 (2006.01); C07D 309/10 (2006.01); C07D 311/12 (2006.01); C07D 333/16 (2006.01); C07D 333/62 (2006.01); C07D 235/06 (2006.01); C07D 405/12 (2006.01); C07D 407/12 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 205/04 (2006.01); C07D 265/30 (2006.01); C07D 277/22 (2006.01); C07D 209/04 (2006.01); C07D 277/62 (2006.01); C07D 295/12 (2006.01); C07D 213/46 (2006.01); C07D 213/64 (2006.01); C07D 307/79 (2006.01); C07B 59/00 (2006.01); C07D 213/56 (2006.01); C07D 213/61 (2006.01); C07D 235/08 (2006.01); C07D 277/30 (2006.01); C07D 295/13 (2006.01); C07D 305/08 (2006.01); C07D 307/81 (2006.01); C07D 309/12 (2006.01); C07D 311/58 (2006.01); C07D 333/24 (2006.01); C07D 333/60 (2006.01); C07D 405/06 (2006.01); C07D 471/08 (2006.01); C07D 487/08 (2006.01);
U.S. Cl.
CPC ...
C07D 319/18 (2013.01); C07B 59/002 (2013.01); C07D 205/04 (2013.01); C07D 209/04 (2013.01); C07D 211/46 (2013.01); C07D 213/46 (2013.01); C07D 213/56 (2013.01); C07D 213/61 (2013.01); C07D 213/64 (2013.01); C07D 215/06 (2013.01); C07D 231/56 (2013.01); C07D 235/06 (2013.01); C07D 235/08 (2013.01); C07D 265/30 (2013.01); C07D 277/22 (2013.01); C07D 277/30 (2013.01); C07D 277/62 (2013.01); C07D 295/12 (2013.01); C07D 295/13 (2013.01); C07D 305/08 (2013.01); C07D 307/79 (2013.01); C07D 307/81 (2013.01); C07D 309/10 (2013.01); C07D 309/12 (2013.01); C07D 311/12 (2013.01); C07D 311/58 (2013.01); C07D 333/16 (2013.01); C07D 333/24 (2013.01); C07D 333/60 (2013.01); C07D 333/62 (2013.01); C07D 405/06 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 407/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 471/08 (2013.01); C07D 487/08 (2013.01); C07D 491/056 (2013.01); C07B 2200/05 (2013.01); C07B 2200/07 (2013.01);
Abstract

Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).


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