The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2019
Filed:
Apr. 24, 2017
Applicant:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Inventors:
Wenjin Yang, Foster City, CA (US);
Che-Hong Chen, Fremont, CA (US);
Daria Mochly-Rosen, Menlo Park, CA (US);
Assignee:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/02 (2006.01); A61K 31/44 (2006.01); C07D 213/82 (2006.01); C07D 213/81 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07C 311/16 (2006.01); C07C 311/17 (2006.01); C07C 311/29 (2006.01); C07C 311/40 (2006.01); C07C 317/32 (2006.01); C07C 233/66 (2006.01); C07C 233/73 (2006.01); C07C 233/78 (2006.01); C07C 233/87 (2006.01); C07C 235/60 (2006.01); C07C 237/32 (2006.01); C07C 235/48 (2006.01); C07D 213/89 (2006.01); C07D 317/58 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 213/82 (2013.01); C07C 233/66 (2013.01); C07C 233/73 (2013.01); C07C 233/78 (2013.01); C07C 233/87 (2013.01); C07C 235/48 (2013.01); C07C 235/60 (2013.01); C07C 237/32 (2013.01); C07C 311/16 (2013.01); C07C 311/17 (2013.01); C07C 311/29 (2013.01); C07C 311/40 (2013.01); C07C 317/32 (2013.01); C07D 213/81 (2013.01); C07D 213/89 (2013.01); C07D 317/58 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07C 2601/02 (2017.05); C07C 2601/04 (2017.05); C07C 2601/08 (2017.05);
Abstract
The present disclosure provides compounds of formula (I) that function as modulators of mitochondrial aldehyde dehydrogenase-2 (ALDH2) activity, and methods of preparing these compounds.