The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2019
Filed:
Jun. 02, 2015
Applicant:
Osaka University, Suita-shi, Osaka, JP;
Inventors:
Nao Jonai, Tokyo, JP;
Yukako Fujinaga, Osaka, JP;
Masahiro Yutani, Osaka, JP;
Yo Sugawara, Osaka, JP;
Takuhiro Matsumura, Osaka, JP;
Assignee:
Osaka University, Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/02 (2006.01); A61K 39/08 (2006.01); A61K 39/09 (2006.01); A61K 39/04 (2006.01); A61K 39/39 (2006.01); A61K 39/095 (2006.01); A61K 39/102 (2006.01); A61K 39/12 (2006.01); A61K 39/125 (2006.01); A61K 39/13 (2006.01); A61K 39/145 (2006.01); A61K 39/15 (2006.01); A61K 39/155 (2006.01); A61K 39/165 (2006.01); A61K 39/20 (2006.01); A61K 39/21 (2006.01); A61K 39/215 (2006.01); A61K 39/235 (2006.01); A61K 39/245 (2006.01); A61K 39/25 (2006.01); A61K 39/29 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 39/02 (2013.01); A61K 39/04 (2013.01); A61K 39/08 (2013.01); A61K 39/09 (2013.01); A61K 39/095 (2013.01); A61K 39/102 (2013.01); A61K 39/12 (2013.01); A61K 39/125 (2013.01); A61K 39/13 (2013.01); A61K 39/145 (2013.01); A61K 39/15 (2013.01); A61K 39/155 (2013.01); A61K 39/165 (2013.01); A61K 39/20 (2013.01); A61K 39/21 (2013.01); A61K 39/215 (2013.01); A61K 39/235 (2013.01); A61K 39/245 (2013.01); A61K 39/25 (2013.01); A61K 39/29 (2013.01); A61K 2039/541 (2013.01); A61K 2039/543 (2013.01); A61K 2039/55516 (2013.01); Y02A 50/386 (2018.01); Y02A 50/39 (2018.01); Y02A 50/466 (2018.01); Y02A 50/472 (2018.01);
Abstract
An object of the present invention is to provide an adjuvant for a mucosal vaccine with high safety that induces a sufficient immune response in a mucosal membrane. According to the present invention, an adjuvant for a mucosal vaccine containing a protein complex composed of hemagglutinin (HA) subcomponents HA1 and HA2, and mutant subcomponent HA3 of botulinum toxin is provided.