The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2019
Filed:
Jan. 27, 2016
Applicant:
Scipharm Sàrl, Luxembourg, LU;
Inventors:
Assignee:
SCIPHARM SÀRL, Luxembourg, LU;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); A61K 35/12 (2015.01); A61K 35/28 (2015.01); C12N 5/077 (2010.01); A61K 31/403 (2006.01); A61K 31/497 (2006.01); A61K 31/506 (2006.01); A61K 31/519 (2006.01); A61K 31/522 (2006.01); C12N 5/0789 (2010.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/40 (2013.01); A61K 31/403 (2013.01); A61K 31/497 (2013.01); A61K 31/506 (2013.01); A61K 31/522 (2013.01); A61K 35/28 (2013.01); C12N 5/0647 (2013.01); C12N 5/0669 (2013.01); A61K 2035/124 (2013.01); C12N 2501/01 (2013.01); C12N 2501/02 (2013.01); C12N 2501/734 (2013.01);
Abstract
The present invention provides the new use of composition comprising at least one inhibitor of dipeptidyl peptidase IV (DPP-IV) for increasing migration and homing of haematopoetic progenitor cells in stem cell transplanted recipients, wherein said haematopoetic stem and/or progenitor cells had been treated in vitro with an engraftment enhancing compound, specifically with a prostacyclin analog and a cAMP enhancer before transplantation.