The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2019
Filed:
Nov. 08, 2016
Fondazione Istituto Italiano Di Tecnologia, Genoa, IT;
The Regents of the University of California, Oakland, CA (US);
Daniele Piomelli, Irvine, CA (US);
Chiara Pagliuca, Arezzo, IT;
Daniela Pizzirani, Genoa, IT;
Anders Bach, Valby, DK;
Natalia Realini, Valmorea, IT;
Marco De Vivo, Genoa, IT;
The Regents of the University of California, Oakland, CA (US);
Fondazione Istituto Italiano di Tecnologia, Genoa, IT;
Abstract
The present invention relates to benzoxazolone derivatives as acid ceramidase inhibitors, pharmaceutical compositions containing these inhibitors and methods of inhibiting acid ceramidase for the treatment of disorders in which modulation of the levels of ceramide is clinically relevant. The invention also provides benzoxazolone derivatives for use as a medicament in the treatment of cancer, inflammation, pain, inflammatory pain or pulmonary diseases.