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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10226449 B1

PDFFull Text
Date of Patent:
Mar. 12, 2019

Filed:

Dec. 19, 2014

Heterocyclic modulators of lipid synthesis and combinations thereof

Applicant:

3-v Biosciences, Inc., Menlo Park, CA (US);

Inventors:

Timothy Sean Heuer, Menlo Park, CA (US);

Johan D. Oslob, Menlo Park, CA (US);

Robert S. McDowell, Menlo Park, CA (US);

Russell Johnson, Menlo Park, CA (US);

Hanbiao Yang, Menlo Park, CA (US);

Marc Evanchik, Menlo Park, CA (US);

Cristiana A. Zaharia, Menlo Park, CA (US);

Haiying Cai, Menlo Park, CA (US);

Lily W. Hu, Menlo Park, CA (US);

Gregory Duke, Menlo Park, CA (US);

Yamini Ohol-Gupta, Menlo Park, CA (US);

Marie O'Farrell, Menlo Park, CA (US);

Assignee:

3-V Biosciences, Inc., Menlo Park, CA (US);

Attorney:

Cooley LLP

Primary Examiner:

Nizal S Chandrakumar

Int. Cl.
CPC ...
A61K 31/4178 (2006.01); A61K 31/4155 (2006.01); A61K 31/422 (2006.01); C07D 401/10 (2006.01); C07D 403/10 (2006.01); C07D 403/14 (2006.01); C07D 407/14 (2006.01); A61K 31/337 (2006.01); A61K 31/4196 (2006.01); A61K 31/437 (2006.01); A61K 31/445 (2006.01); A61K 31/453 (2006.01); A61K 31/454 (2006.01); A61K 31/5377 (2006.01); A61K 31/55 (2006.01); A61K 31/4525 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4178 (2013.01); A61K 31/337 (2013.01); A61K 31/4155 (2013.01); A61K 31/4196 (2013.01); A61K 31/422 (2013.01); A61K 31/437 (2013.01); A61K 31/445 (2013.01); A61K 31/453 (2013.01); A61K 31/454 (2013.01); A61K 31/4525 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/5377 (2013.01); A61K 31/55 (2013.01); C07D 401/10 (2013.01); C07D 403/10 (2013.01); C07D 403/14 (2013.01); C07D 407/14 (2013.01);
Abstract

Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by dysregulation of a fatty acid synthase pathway by the administration of such compounds and combinations of such compounds and other therapeutic agents.

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