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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10226426 B1

PDFFull Text
Date of Patent:
Mar. 12, 2019

Filed:

Mar. 01, 2016

Suspension containing nano-cocrystal and manufacturing method

Applicant:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Inventors:

Masatoshi Karashima, Kanagawa, JP;

Katsuhiko Yamamoto, Kanagawa, JP;

Takashi Kojima, Kanagawa, JP;

Yukihiro Ikeda, Kanagawa, JP;

Assignee:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Attorneys:

Anne M. Reynolds

Casimir Jones, S.C.

Primary Examiner:

Carlos A Azpuru

Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 47/16 (2006.01); A61K 47/18 (2017.01); A61K 47/20 (2006.01); A61K 47/22 (2006.01); A61K 47/32 (2006.01); A61K 47/34 (2017.01); A61K 9/10 (2006.01); A61K 47/38 (2006.01); A61K 31/341 (2006.01); A61K 31/405 (2006.01); A61K 31/55 (2006.01); A61K 31/522 (2006.01); A61K 9/16 (2006.01);
U.S. Cl.
CPC ...
A61K 9/146 (2013.01); A61K 9/10 (2013.01); A61K 9/145 (2013.01); A61K 9/1617 (2013.01); A61K 9/1623 (2013.01); A61K 9/1652 (2013.01); A61K 31/341 (2013.01); A61K 31/405 (2013.01); A61K 31/522 (2013.01); A61K 31/55 (2013.01); A61K 47/16 (2013.01); A61K 47/18 (2013.01); A61K 47/20 (2013.01); A61K 47/22 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01); A61K 47/38 (2013.01);
Abstract

The present invention provides a method of producing a suspension containing a nano-cocrystal having an average particle size of not more than 300 nm, a polymer having a number average molecular weight of not less than 3,000, a surfactant having a number average molecular weight of less than 3,000 and water, which method including wet grinding a cocrystal, which is constituted of an organic compound and a cocrystal former and is not dissociated by wet grinding, in water containing the polymer and the surfactant.

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