The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2019
Filed:
Aug. 10, 2013
Mylisa Parette, Bellefonte, PA (US);
Danielle Asquino, Philipsburg, PA (US);
Kari Eyer, Sinking Spring, PA (US);
James Adair, State College, PA (US);
Jeff Davidson, Boalsburg, PA (US);
Mark Kester, Harrisburg, PA (US);
Mylisa Parette, Bellefonte, PA (US);
Danielle Asquino, Philipsburg, PA (US);
Kari Eyer, Sinking Spring, PA (US);
James Adair, State College, PA (US);
Jeff Davidson, Boalsburg, PA (US);
Mark Kester, Harrisburg, PA (US);
Other;
Abstract
Stable, non-toxic, calcium phosphate nanoparticles are formed that incorporate one or more oligonucleotides. RNAi nucleotides may be incorporated and, in particular, siRNA nucleotides. Since the siRNA nanoparticles dissociate leaving only naturally occurring residual materials, calcium and phosphate, along with the siRNA, they are particularly useful as carrier vehicles. The ability to incorporate more than one siRNA provides a means to block or knock down the translation of multiple targeted proteins at the same time.