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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10222377 B1

PDFFull Text
Date of Patent:
Mar. 05, 2019

Filed:

Jan. 19, 2012

Use of bubr1 as a biomarker of drug response to furazanobenzimidazoles

Applicants:

Heidi Alexandra Lane, Therwil, CH;

Felix Bachmann, Basel, CH;

Madlaina Breuleux, Basel, CH;

Michael Boutros, Heidelberg, DE;

Daniel Gilbert, Heidelberg, DE;

Xian Zhang, Heidelberg, DE;

Inventors:

Heidi Alexandra Lane, Therwil, CH;

Felix Bachmann, Basel, CH;

Madlaina Breuleux, Basel, CH;

Michael Boutros, Heidelberg, DE;

Daniel Gilbert, Heidelberg, DE;

Xian Zhang, Heidelberg, DE;

Assignees:

BASILEA PHARMACEUTICA AG, Basel, CH;

RUPRECHT-KARLS-UNIVERSITAT-HEIDELBERG, Heidelberg, DE;

Attorney:
Primary Examiner:

Shirley V Gembeh

Int. Cl.
CPC ...
G01N 33/50 (2006.01); C12Q 1/6886 (2018.01); G01N 33/574 (2006.01); A61K 31/4245 (2006.01); A61K 31/4439 (2006.01); A61K 31/44 (2006.01); A61K 31/41 (2006.01); C12Q 1/68 (2006.01); G01N 33/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57484 (2013.01); A61K 31/4245 (2013.01); A61K 31/4439 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5011 (2013.01); G01N 33/5026 (2013.01); G01N 33/57496 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/91205 (2013.01); G01N 2800/44 (2013.01); G01N 2800/52 (2013.01);
Abstract

Use of BUBR1 as a biomarker for predicting the response to a compound, preferably resistance of a disease such as cancer in a subject, wherein the compound is a furazanobenzimidazole compound of general formula (I).

Find Patent Forward Citations

Lane, Heidi. (2019). Use of bubr1 as a biomarker of drug response to furazanobenzimidazoles (U.S. Patent No. 10222377). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10222377

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