The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 2019

Filed:

Jul. 14, 2017
Applicants:

Scott E. Gygax, Yardley, PA (US);

Sean Chadwick, Florence, NJ (US);

Aditya Prasad, Marlton, NJ (US);

Martin E. Adelson, East Windsor, NJ (US);

Eli Mordechai, Robbinsville, NJ (US);

Inventors:

Scott E. Gygax, Yardley, PA (US);

Sean Chadwick, Florence, NJ (US);

Aditya Prasad, Marlton, NJ (US);

Martin E. Adelson, East Windsor, NJ (US);

Eli Mordechai, Robbinsville, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/689 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/689 (2013.01); C12Q 2600/156 (2013.01);
Abstract

The present invention is based on the discovery of polymorphisms (SNPs) in the penicillin binding protein (pbp3) gene in. The presence of G88A and/or G2047A SNPs provides an accurate, reliable biomarker for the presence of Methicillin Resistant(MRSA), specifically the community-associated MRSA (CA-MRSA). The present invention provides reagents used for detecting the SNPs as well as methods of identifying and using these variants to screen subjects for presence of CA-MRSA. The methods involve isolating a biological sample from a mammal (preferably a human) and testing for the presence of a SNP in the pbp3 gene which is associated with CA-MRSA.


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