The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 2019

Filed:

Apr. 26, 2017
Applicant:

Cellular Dynamics International, Inc., Madison, WI (US);

Inventors:

Matthew Brown, Madison, WI (US);

Elizabeth Rondon Dominguez, Madison, WI (US);

Randy Learish, Oregon, WI (US);

Emile Nuwaysir, Madison, WI (US);

Deepika Rajesh, Madison, WI (US);

Amanda Mack, Madison, WI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); C12N 15/00 (2006.01); C12N 5/074 (2010.01); C12N 15/85 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); C12N 15/85 (2013.01); C12N 15/86 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/515 (2013.01); C12N 2501/602 (2013.01); C12N 2501/603 (2013.01); C12N 2501/604 (2013.01); C12N 2501/605 (2013.01); C12N 2501/606 (2013.01); C12N 2501/608 (2013.01); C12N 2506/11 (2013.01); C12N 2740/10043 (2013.01); C12N 2830/20 (2013.01);
Abstract

Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may be generated from CD34hematopoietic cells, such as human CD34blood progenitor cells, or T cells. Various iPS cell lines are also provided. In certain embodiments, the invention provides novel induced pluripotent stem cells with a genome comprising genetic rearrangement of T cell receptors.


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