The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 2019

Filed:

Apr. 21, 2011
Applicants:

Motoichi Kurisawa, Singapore, SG;

LI Shan Wang, Singapore, SG;

Joo Eun Chung, Singapore, SG;

Inventors:

Motoichi Kurisawa, Singapore, SG;

Li Shan Wang, Singapore, SG;

Joo Eun Chung, Singapore, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08B 37/08 (2006.01); A61K 47/48 (2006.01); C08H 1/06 (2006.01); C08J 3/075 (2006.01); C08J 3/24 (2006.01); C08L 5/02 (2006.01); C08L 5/08 (2006.01); C08L 71/02 (2006.01); C08L 89/00 (2006.01); C12N 5/00 (2006.01); C08L 89/06 (2006.01);
U.S. Cl.
CPC ...
C08B 37/0072 (2013.01); A61K 47/48038 (2013.01); A61K 47/48292 (2013.01); C08H 1/06 (2013.01); C08J 3/075 (2013.01); C08J 3/246 (2013.01); C08L 5/02 (2013.01); C08L 5/08 (2013.01); C08L 71/02 (2013.01); C08L 89/00 (2013.01); C12N 5/0068 (2013.01); C08L 89/06 (2013.01); C12N 2533/54 (2013.01); C12N 2533/80 (2013.01); C12N 2537/10 (2013.01);
Abstract

A composite is disclosed. The composite comprises a first conjugate of a polymer and a first phenol-containing moiety, and a second conjugate of a gelatin or collagen and a second phenol-containing moiety, wherein the polymer is selected so that the first conjugate is less cell-adhesive than the second conjugate, at least one of the first and second conjugates is crosslinked to form a matrix, and the composite comprises discrete regions that are rich in one of said first and second conjugates. A method of forming such composite is also disclosed. The method comprises mixing precursors for the first and second conjugates in a solution for forming said composite, and dispersing a catalyst in the solution to catalyze crosslinking of at least one of the first and second conjugates to form the matrix. The composite may be used to grow cells.


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