The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 2019

Filed:

Jan. 12, 2017
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Ray Camphausen, Wayland, MA (US);

David Fabrizio, South Hamilton, MA (US);

Martin C. Wright, Belmont, MA (US);

Patrick Gage, Bryn Mawr, PA (US);

John Mendlein, Encinitas, CA (US);

Assignee:

BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/78 (2006.01); C07K 14/47 (2006.01); C07K 14/71 (2006.01); A61K 38/39 (2006.01); A61K 39/395 (2006.01); C07K 19/00 (2006.01); C12N 15/10 (2006.01); C40B 30/04 (2006.01); C40B 40/08 (2006.01); A61K 38/18 (2006.01); C07K 14/00 (2006.01); C07K 14/765 (2006.01); C07K 14/79 (2006.01); C07K 16/00 (2006.01); A61K 47/60 (2017.01); A61K 47/64 (2017.01); A61K 47/68 (2017.01); C07K 16/22 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01); C40B 40/10 (2006.01);
U.S. Cl.
CPC ...
C07K 14/78 (2013.01); A61K 38/18 (2013.01); A61K 38/39 (2013.01); A61K 47/60 (2017.08); A61K 47/643 (2017.08); A61K 47/644 (2017.08); A61K 47/68 (2017.08); C07K 14/00 (2013.01); C07K 14/765 (2013.01); C07K 14/79 (2013.01); C07K 16/00 (2013.01); C12N 15/1062 (2013.01); C40B 30/04 (2013.01); C40B 40/08 (2013.01); A61K 39/3955 (2013.01); A61K 2039/505 (2013.01); C07K 14/47 (2013.01); C07K 14/71 (2013.01); C07K 16/2863 (2013.01); C07K 19/00 (2013.01); C07K 2317/92 (2013.01); C07K 2319/30 (2013.01); C07K 2319/74 (2013.01); C40B 40/10 (2013.01);
Abstract

The present invention provides innovative proteins that bind to insulin-like growth factor-I receptor (IGF-IR), as well as other important proteins. The invention also provides innovative proteins in pharmaceutical preparations and derivatives of such proteins and the uses of same in diagnostic, research and therapeutic applications. The invention further provides cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and vectors comprising the polynucleotides encoding the innovative proteins.


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