The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 2019

Filed:

Jun. 10, 2015
Applicant:

Gilead Sciences, Inc., Foster City, CA (US);

Inventors:

Zhimin Du, Belmont, CA (US);

Jerry Evarts, Seattle, WA (US);

Joshua Kaplan, Foster City, CA (US);

Musong Kim, Bothell, WA (US);

Devan Naduthambi, San Bruno, CA (US);

Leena Patel, Mercer Island, WA (US);

Stephane Perreault, Brier, WA (US);

Barton W. Phillips, San Mateo, CA (US);

Gary Phillips, Issaquah, WA (US);

Kirk L. Stevens, Bothell, WA (US);

Jennifer A. Treiberg, Redmond, WA (US);

Joshua Van Veldhuizen, Seattle, WA (US);

William J. Watkins, Saratoga, CA (US);

Suet Chung Yeung, Redmond, WA (US);

Assignee:

Gilead Sciences, Inc., Foster City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/04 (2006.01); C07D 403/12 (2006.01); C07D 413/14 (2006.01); C07D 403/14 (2006.01); C07D 239/91 (2006.01); C07D 487/04 (2006.01); C07D 401/14 (2006.01); C07D 473/34 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); C07D 239/91 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 413/14 (2013.01); C07D 473/34 (2013.01); C07D 487/04 (2013.01);
Abstract

The present application provides the compounds of formula (J), or pharmaceutically acceptable salts, isomers, or a mixture thereof, wherein n, m, q, A', W, W, W, R, R, and Rare described herein. The compounds are inhibitors to the activities of phosphatidylinositol 3-kinase (PI3K) and are useful for treating conditions mediated by one or more PI3K isoforms. The present application further provides pharmaceutical compositions that include a compound of formula (J), or pharmaceutically acceptable salts, isomers, tautomer, or mixture thereof, and methods of using these compounds and compositions for treating conditions mediated by one or more PI3K isoforms.


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