The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 2019
Filed:
Aug. 14, 2015
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Kristos Adrian Moshos, Belmont, MA (US);
Valdas Jurkauskas, Cambridge, MA (US);
Giovanni Fogliato, Barzana, IT;
Manuel Scanu, Milan, IT;
You Seok Hwang, Windham, NH (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
Described herein are crystalline forms of a compound of formula (IIΓ), including toluene solvates off A TD-CLE, as well as processes for the preparation thereof and use thereof in the preparation of cephalosporin compounds such as ceftolozane. Provided herein is a crystalline form of a compound of formula (IIΓ): wherein X is CI, Br, or I; and R1 and R2 are each independently an oxygen protecting group; processes for making the crystalline form, and use of said form in the synthesis of antibacterial cephalosporins such as ceftolozane.