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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10221142 B1

PDFFull Text
Date of Patent:
Mar. 05, 2019

Filed:

Feb. 11, 2016

Substituted pyrazole compounds as rorgammat inhibitors and uses thereof

Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Blair T. Lapointe, Boston, MA (US);

Peter H. Fuller, Boston, MA (US);

Hakan Gunaydin, Boston, MA (US);

Kun Liu, Boston, MA (US);

Nunzio Sciammetta, Boston, MA (US);

Benjamin Wesley Trotter, Boston, MA (US);

Hongjun Zhang, Boston, MA (US);

Kenneth J. Barr, Boston, MA (US);

John K. F. Maclean, Kilmarnock, GB;

Danielle F. Molinari, Brookline, MA (US);

Vladimir Simov, South Boston, MA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorney:

Dechert LLP

Primary Examiner:

Kamal A Saeed

Int. Cl.
CPC ...
C07D 231/56 (2006.01); C07D 487/04 (2006.01); A61K 45/06 (2006.01); A61K 31/416 (2006.01); C07D 471/04 (2006.01); C07D 491/052 (2006.01); C07D 491/107 (2006.01); C07D 495/04 (2006.01); C07D 403/12 (2006.01); C07D 487/14 (2006.01); C07D 405/12 (2006.01); C07D 413/06 (2006.01); C07D 487/06 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 231/56 (2013.01); A61K 31/416 (2013.01); A61K 45/06 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 413/06 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 487/06 (2013.01); C07D 487/14 (2013.01); C07D 491/052 (2013.01); C07D 491/107 (2013.01); C07D 495/04 (2013.01); C07D 513/04 (2013.01); A61K 2300/00 (2013.01);
Abstract

The present invention relates to compounds according to Formula (I-1) and pharmaceutically acceptable salts thereof. Such compounds can be used in the treatment of RORgammaT-mediated diseases or conditions.

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Lapointe, Blair. (2019). Substituted pyrazole compounds as rorgammat inhibitors and uses thereof (U.S. Patent No. 10221142). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10221142

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