The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 2019
Filed:
Apr. 29, 2014
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Humboldt-universitat Zu Berlin, Berlin, DE;
Karl A. Deisseroth, Palo Alto, CA (US);
Emily Anne Ferenczi, Stanford, CA (US);
Peter Hegemann, Falkensee, DE;
The Board of Trustees of The Leland Stanford Junior University, Stanford, CA (US);
HUMBOLDT-UNIVERSITAT ZU BERLIN, Berlin, DE;
Abstract
Aspects of the disclosure include devices, systems and methods for optogenetic modulation of action potentials in target cells. The subject devices include light-generating devices, control devices, and delivery devices for delivering vectors to target cells. The subject systems include light-activated proteins, response proteins, nucleic acids comprising nucleotide sequences encoding these proteins, as well as expression systems that facilitate expression of these proteins in target cells. Also provided are methods of using the subject devices and systems to optogenetically inhibit and intercept action potentials in target cells, e.g., to treat a neurological or psychiatric condition in a human or non-human animal subject.