The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 2019
Filed:
Dec. 18, 2015
Oregon Health & Science University, Portland, OR (US);
Sanofi Pasteur, Inc., Swiftwater, PA (US);
Ted Milburn Ross, Watkinsville, GA (US);
Tim Alefantis, Springbrook Township, PA (US);
Donald Martin Carter, Athens, GA (US);
Christopher Austin Darby, Port Saint Lucie, FL (US);
Harold Kleanthous, Chelmsford, MA (US);
OREGON HEALTH & SCIENCE UNIVERSITY, Portland, OR (US);
SANOFI PASTEUR, INC., Swiftwater, PA (US);
Abstract
The present invention provides co-administration (for example, immunogenic cocktail compositions and/or prime-boost regimens) of computationally optimized H1N1 influenza hemagglutinin (HA) polypeptides. Co-administration of the optimized H1N1 influenza hemagglutinin (HA) polypeptides facilitates synergistic neutralization of viral infection and provides for improved protective immunity (e.g., a broad reactive immune response) to diverse and multiple H1N1 influenza virus strains, including both seasonal and pandemic strains.