The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 2019
Filed:
Feb. 07, 2014
Applicant:
LA Jolla Institute for Allergy and Immunology, La Jolla, CA (US);
Inventors:
Carl F. Ware, Solana Beach, CA (US);
Timothy C. Cheung, Wollstonecraft, AU;
Marcos Steinberg, San Diego, CA (US);
Assignee:
LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0005 (2013.01); C07K 16/2803 (2013.01); C07K 16/2818 (2013.01); C07K 16/2878 (2013.01); C07K 2317/73 (2013.01); C07K 2317/74 (2013.01); C07K 2317/75 (2013.01); C07K 2317/76 (2013.01); C07K 2319/30 (2013.01); G01N 2333/70578 (2013.01);
Abstract
The invention provides HVEM cis complexes which include, for example, HVEM/BTLA, HVEM/CD160 and HVEM/gD cis complexes. The invention provides ligands and agents that bind to HVEM cis complexes, such as antibodies. The invention further provides methods of use of the HVEM cis complexes, and the ligands and agents (e.g., LIGHT polypeptide sequence) that bind to the HVEM cis complexes.