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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10220048 B1

PDFFull Text
Date of Patent:
Mar. 05, 2019

Filed:

Nov. 18, 2016

Compositions and methods for treating ocular diseases

Applicant:

Aerpio Therapeutics, Inc., Cincinnati, OH (US);

Inventors:

Kevin Peters, Cincinnati, OH (US);

Robert Shalwitz, Bexley, OH (US);

Assignee:

AERPIO THERAPEUTICS, INC., Cincinnati, OH (US);

Attorney:

Wilson Sonsini Goodrich & Rosati

Primary Examiner:

Kortney L Klinkel

Assistant Examiner:

William Y Lee

Int. Cl.
CPC ...
A61K 31/635 (2006.01); A61K 31/04 (2006.01); A61K 31/10 (2006.01); C07D 277/22 (2006.01); A61K 39/395 (2006.01); A61K 31/426 (2006.01); A61K 31/427 (2006.01); A61K 31/497 (2006.01); A61K 31/4439 (2006.01); A61K 31/428 (2006.01); A61K 31/496 (2006.01); A61K 31/513 (2006.01); A61K 31/538 (2006.01); C07D 277/52 (2006.01); C07D 417/04 (2006.01); C07D 277/64 (2006.01); C07K 16/22 (2006.01); A61K 38/05 (2006.01); A61K 47/40 (2006.01); C07D 413/04 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 263/32 (2006.01); C07D 277/28 (2006.01); A61K 39/00 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/635 (2013.01); A61K 31/04 (2013.01); A61K 31/10 (2013.01); A61K 31/426 (2013.01); A61K 31/427 (2013.01); A61K 31/428 (2013.01); A61K 31/4439 (2013.01); A61K 31/496 (2013.01); A61K 31/497 (2013.01); A61K 31/513 (2013.01); A61K 31/538 (2013.01); A61K 38/05 (2013.01); A61K 39/3955 (2013.01); A61K 47/40 (2013.01); C07D 263/32 (2013.01); C07D 277/22 (2013.01); C07D 277/28 (2013.01); C07D 277/52 (2013.01); C07D 277/64 (2013.01); C07D 413/04 (2013.01); C07D 417/04 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07K 16/22 (2013.01); A61K 9/0019 (2013.01); A61K 2039/505 (2013.01);
Abstract

Disclosed herein are compositions and methods for treating ocular diseases, inter alia, diabetic macular edema, age-related macular degeneration (wet form), choroidal neovascularization, diabetic retinopathy, retinal vein occlusion (central or branch), ocular trauma, surgery induced edema, surgery induced neovascularization, cystoid macular edema, ocular ischemia, uveitis, and the like. These diseases or conditions are characterized by changes in the ocular vasculature whether progressive or non-progressive, whether a result of an acute disease or condition, or a chronic disease or condition.

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