The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 2019

Filed:

Jul. 22, 2015
Applicant:

National Taiwan University, Taipei, TW;

Inventors:

Tai-Horng Young, Taipei, TW;

Jin-Shing Chen, Taipei, TW;

Hong-Shiee Lai, Taipei, TW;

Ke-Cheng Chen, Taipei, TW;

Ya-Shuan Chou, Taipei, TW;

Yong-Chong Lin, Taipei, TW;

Hao-Ying Hsieh, Taipei, TW;

Hsu-Hsien Chang, Taipei, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 31/06 (2006.01); A61L 31/04 (2006.01); A61B 17/00 (2006.01); A61L 27/18 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); A61L 27/58 (2006.01); A61F 2/00 (2006.01);
U.S. Cl.
CPC ...
A61B 17/0057 (2013.01); A61L 27/18 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); A61B 2017/00004 (2013.01); A61B 2017/0061 (2013.01); A61B 2017/00575 (2013.01); A61B 2017/00597 (2013.01); A61B 2017/00809 (2013.01); A61B 2017/00884 (2013.01); A61B 2017/00893 (2013.01); A61B 2017/00942 (2013.01); A61B 2017/00951 (2013.01); A61F 2/0063 (2013.01); A61F 2210/0004 (2013.01); A61F 2250/0024 (2013.01); A61L 2300/252 (2013.01); A61L 2300/402 (2013.01); A61L 2300/406 (2013.01); A61L 2300/416 (2013.01);
Abstract

The invention relates to a method of treating pleural abnormalities in a subject in need thereof, comprising the steps of: (a) attaching a biodegradable polymeric membrane onto a pleural wound to elicit fibronectin from fibroblasts to cause fibrous adhesion; and (b) securing the membrane with securement products, including sutures, staples, and sealants. The present invention also relates to a biodegradable adhesion membrane used for treating pleural abnormalities, comprising: a biodegradable base material selected from the group consisting of polycaprolactone (PCL), polylactic acid or polylactide (PLA), polyhydroxybutyrate (PHB), poly(ethylene adipate), poly(butylene adipate) (PBA), chitosan, hyaluronic acid, and polyglycolic acid (PGA); wherein the thickness of the membrane is 0.1-1 mm.


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