The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 26, 2019

Filed:

Apr. 15, 2016
Applicant:

Premium Genetics (Uk) Ltd., Stapeley, Nantwich, Cheshire, GB;

Inventors:

Daniel Mueth, Chicago, IL (US);

Joseph Plewa, Park Ridge, IL (US);

Jessica Shireman, Kansas City, MO (US);

Amy Anderson, Palatine, IL (US);

Lewis Gruber, Chicago, IL (US);

Neil Rosenbaum, Chicago, IL (US);

Assignee:

Premium Genetics (UK) LTD, Stapeley, Nantwich, Cheshire, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G03H 1/00 (2006.01); G02B 21/32 (2006.01); H05H 3/04 (2006.01); B01D 21/01 (2006.01); G01N 33/487 (2006.01); G01N 21/64 (2006.01); G01N 33/50 (2006.01); A61L 2/08 (2006.01); B01D 21/26 (2006.01); B03C 1/00 (2006.01); B04B 13/00 (2006.01); G01N 27/447 (2006.01); G21K 5/08 (2006.01); B01L 3/00 (2006.01); G03H 1/08 (2006.01); G03H 1/22 (2006.01); B03C 1/28 (2006.01); B03C 5/00 (2006.01); G01N 15/00 (2006.01); G01N 15/02 (2006.01); B01D 21/00 (2006.01);
U.S. Cl.
CPC ...
G03H 1/0005 (2013.01); A61L 2/08 (2013.01); B01D 21/01 (2013.01); B01D 21/262 (2013.01); B01L 3/502761 (2013.01); B03C 1/00 (2013.01); B04B 13/00 (2013.01); G01N 21/6486 (2013.01); G01N 27/447 (2013.01); G01N 27/44756 (2013.01); G01N 33/487 (2013.01); G01N 33/5091 (2013.01); G02B 21/32 (2013.01); G21K 5/08 (2013.01); H05H 3/04 (2013.01); B01D 21/0009 (2013.01); B01L 2200/0652 (2013.01); B01L 2200/0668 (2013.01); B01L 2300/0864 (2013.01); B01L 2400/0454 (2013.01); B03C 1/002 (2013.01); B03C 1/288 (2013.01); B03C 5/005 (2013.01); G01N 15/0205 (2013.01); G01N 2015/0053 (2013.01); G01N 2201/061 (2013.01); G01N 2458/00 (2013.01); G03H 1/08 (2013.01); G03H 1/2294 (2013.01); G03H 2001/0077 (2013.01); G03H 2001/085 (2013.01); G03H 2225/32 (2013.01);
Abstract

The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.


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