The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 26, 2019
Filed:
Feb. 18, 2016
The United States of America, As Represented BY the Secretary of Homeland Security, Washington, DC (US);
Segaran Pillai, Laurel, MD (US);
Linda Weigel, Decatur, GA (US);
Bernard Quigley, Atlanta, GA (US);
David R. Hodge, Washington, DC (US);
The United States of America, as represented by the Secretary of Homeland Security, Washington, DC (US);
Abstract
Disclosed herein are the identification, cloning, and optimizing the lytic activity of one or more novellysin proteins, a method of selecting a lysin agent for use in molecular diagnostic testing that includes analyzing genome databases forand near neighbors, selecting candidate genes encoding potential lytic enzymes based on conserved amino acid motifs as determined in peptidoglycan hydrolases, cloning the candidate genes in expression vector, isolating proteins thereof, and testing for lytic activity against, and selecting an optimum gene of the candidate genes for optimizing lysis conditions.