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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10214564 B1

PDFFull Text
Date of Patent:
Feb. 26, 2019

Filed:

Feb. 05, 2014

Antimicrobial peptides derived from hepatitis b virus core protein arginine-rich domain

Applicant:

Academia Sinica, Taipei, TW;

Inventors:

Chiaho Shih, Taipei, TW;

Heng-Li Chen, Taipei, TW;

Pei-Yi Su, Taipei, TW;

Assignee:

Academia Sinica, Taipei, TW;

Attorney:

Cesari and McKenna, LLP

Primary Examiner:

Jennifer Pitrak McDonald

Assistant Examiner:

Tara L Martinez

Int. Cl.
CPC ...
C07K 14/005 (2006.01); C12N 7/00 (2006.01); A61K 39/29 (2006.01); A61K 39/12 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 39/12 (2013.01); A61K 39/292 (2013.01); C12N 7/00 (2013.01); A61K 38/00 (2013.01); C12N 2730/10133 (2013.01); C12N 2730/10134 (2013.01);
Abstract

A pharmaceutical composition for use in killing and/or inhibiting the growth and/or proliferation of a microorganism in a subject in need thereof, or for treating a subject afflicted with a microbial infection is disclosed. The composition comprises: (a) an effective amount of an isolated peptide, wherein the peptide comprises the arginine-rich carboxy-terminal region of hepatitis B virus core protein (HBc) and exhibits an antimicrobial activity; and (b) a pharmaceutically acceptable carrier. The peptide exhibits an activity against Gram-negative bacteria, Gram-positive bacteria, and/or fungi.

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Shih, Chiaho. (2019). Antimicrobial peptides derived from hepatitis b virus core protein arginine-rich domain (U.S. Patent No. 10214564). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10214564

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