The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 26, 2019

Filed:

Jan. 06, 2015
Applicant:

Bayer Pharma Aktiengesellschaft, Berlin, DE;

Inventors:

Volker Schulze, OT Bergf, DE;

Knut Eis, Berlin, DE;

Florian Puehler, Wellesley, MA (US);

Ludwig Zorn, Berlin, DE;

Detlev Sülzle, Berlin, DE;

Philip Lienau, Berlin, DE;

Antje Margret Wengner, Berlin, DE;

Kirstin Petersen, Berlin, DE;

Ulf Bömer, Berlin, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/5025 (2006.01); C07D 519/00 (2006.01); C07D 491/04 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61K 31/5025 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 487/04 (2013.01); C07D 491/04 (2013.01);
Abstract

The present invention relates to amido-substituted imidazopyridazine compounds of general formula (I): in which A, E, R2, R3, R4 and n are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.


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