The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 26, 2019
Filed:
Dec. 19, 2014
Institute for Drug Discovery, Llc, Guilford, CT (US);
Michael L. Corman, Salem, CT (US);
William M. Hungerford, Niantic, CT (US);
Adam Golebiowski, Madison, CT (US);
Raymond P. Beckett, Yorktown Heights, NY (US);
Marzena Mazur, Lodz, PL;
Sylwia Olejniczak, Zgierz, PL;
Jacek Olczak, Lodz, PL;
Institute for Drug Discovery, LLC, Guilford, CT (US);
Abstract
The invention provides novel substituted amino triazoles of Formula (I), or a pharmaceutically acceptable salt, hydrate or solvate thereof, as well as pharmaceutical compositions comprising the same. The compounds of the invention are inhibitors of acidic mammalian chitinase (AMCase) and are useful, in a non-limiting embodiment, for treating asthma. The invention further provides methods of using compounds and/or compositions of the invention to treat asthma and/or to monitor asthma treatment.