The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 26, 2019

Filed:

Aug. 31, 2015
Applicant:

National Cheng Kung University, Tainan, TW;

Inventors:

Dar-Bin Shieh, Tainan, TW;

Chih-Chia Huang, Tainan, TW;

Chen-Min Chang, Tainan, TW;

Tsung-Ju Li, Tainan, TW;

Po-Yang Chang, Tainan, TW;

Ming-Chi Hsieh, Tainan, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12P 19/34 (2006.01); B01L 7/00 (2006.01); C01G 49/08 (2006.01); B01L 9/06 (2006.01);
U.S. Cl.
CPC ...
B01L 7/52 (2013.01); C01G 49/08 (2013.01); B01L 9/06 (2013.01); B01L 2200/0647 (2013.01); B01L 2200/147 (2013.01); B01L 2300/023 (2013.01); B01L 2300/027 (2013.01); B01L 2300/1844 (2013.01); B01L 2300/1861 (2013.01); C01P 2004/62 (2013.01); C01P 2004/64 (2013.01); C01P 2006/32 (2013.01);
Abstract

Method and apparatus for amplifying a target nucleic acid sequence of a reaction mixture in a Polymerase Chain Reaction (PCR). The method includes contacting the reaction mixture with EMR frequency absorbing particles formed from a material having a transition metal, transition metal oxide or a transition metal hydroxide, or a nitride, a phosphide or an arsenide of a Group III metal doped with the transition metal or a transition metal oxide, or silicon dioxide doped with the transition metal, transition metal oxide, or transition metal hydroxide; and irradiating the EMR absorbing particles with EMR having a frequency of about 200 kHz to 500 THz to amplify the target nucleic acid sequence, wherein the Group III metal is any one of Al, Ga, and In, and the transition metal is any one of Mn, Fe, Co and Cu.


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