The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 26, 2019

Filed:

Sep. 02, 2015
Applicant:

Fraunhofer-gesellschaft Zur Foerderung Der Angewandten Forschung E.v., Munich, DE;

Inventors:

Holger Spiegel, Aachen, DE;

Alexander Boes, Cologne, DE;

Gueven Edgue, Aachen, DE;

Veronique Beiss, Aachen, DE;

Markus Sack, Alsdorf, DE;

Andreas Reimann, Krefeld, DE;

Rainer Fischer, Aachen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/015 (2006.01); C07K 14/445 (2006.01); C12N 15/62 (2006.01); C07K 16/20 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/015 (2013.01); C07K 14/445 (2013.01); C07K 16/205 (2013.01); C12N 15/62 (2013.01); A61K 2039/575 (2013.01); A61K 2039/64 (2013.01); A61K 2039/70 (2013.01); C07K 2319/00 (2013.01); C07K 2319/40 (2013.01); Y02A 50/412 (2018.01);
Abstract

The technology provided herein relates to novel malaria vaccines composed of different recombinant proteins, in particular recombinant fusion proteins comprising several differentantigens from the pre-erythrocytic, the blood, and the sexual parasite main stages. The proteins may be used in a mixture vaccine formulation to elicit protective immune responses in humans. Nucleic acid molecules encoding said recombinant proteins, vectors and host cells containing the nucleic acids and methods for preparation and producing such proteins are also disclosed, as well as antibodies induced or generated by the use of said malaria vaccines and the use of such antibodies or recombinant derivatives for passive immunotherapy.


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