The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 26, 2019
Filed:
Jan. 13, 2012
Michael Freissmuth, Vienna, AT;
Eva-maria Zebedin-brandl, Vienna, AT;
Christian Bergmayr, Vienna, AT;
Filza Hussain, Vienna, AT;
Michael Freissmuth, Vienna, AT;
Eva-Maria Zebedin-Brandl, Vienna, AT;
Christian Bergmayr, Vienna, AT;
Filza Hussain, Vienna, AT;
SCIPHARM SARL, Mertert, LU;
Abstract
The present invention provides a novel method for enhancing engraftment of haematopoetic stem cells by an ex-vivo pretreatment comprising the steps of obtaining a sample containing haematopoetic stem cells and admixing a prostacyclin analog to obtain a mixture, incubating said mixture for a period of time sufficient to stimulate G alphas-signalling in said cells and optionally and isolating said stimulated cells. Further, a composition comprising a prostacyclin analog for use in the treatment of individuals undergoing haematopoetic stem cell transplantation is provided.