The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 26, 2019

Filed:

Sep. 24, 2014
Applicants:

Technische Universiteit Eindhoven, AZ Eindhoven, NL;

Universitaet Zuerich, Zurich, CH;

Inventors:

Bart Sanders, SP Eindhoven, NL;

Sandra Vossen-Loerakker, GL Eindhoven, NL;

Anita Driessen-Mol, JM Rosmalen, NL;

Simon Philipp Hoerstrup, Zurich, CH;

Franciscus Petrus Thomas Baaijens, DB Eindhoven, NL;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/00 (2006.01); A61F 2/24 (2006.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12M 3/00 (2006.01);
U.S. Cl.
CPC ...
A61F 2/2415 (2013.01); C12M 21/08 (2013.01); C12M 25/00 (2013.01); C12M 29/04 (2013.01); A61F 2/0077 (2013.01); A61F 2/2472 (2013.01);
Abstract

Various inserts, called shapers and spacers, are provided for controlling tissue engineered heart valve (TEHV) leaflet geometry during culture. These inserts will prevent TEHV leaflet retraction during culture, be able to control the leaflet geometry during culture, enable culturing TEHV leaflets with a larger coaptation area, control the height of the coaptation area, maintain TEHV leaflet curvatures, and/or enable possibilities to culture TEHV leaflets in open configuration.


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