The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2019

Filed:

Aug. 10, 2012
Applicants:

Tim Maguire, Piscataway, NJ (US);

Martin L. Yarmush, Newton, MA (US);

Rene S. Schloss, East Brunswick, NJ (US);

Bhaskar Mitra, Pradesh, IN;

Rohit Jindal, Braintree, MA (US);

Mehdi Ghodbane, Piscataway, NJ (US);

Inventors:

Tim Maguire, Piscataway, NJ (US);

Martin L. Yarmush, Newton, MA (US);

Rene S. Schloss, East Brunswick, NJ (US);

Bhaskar Mitra, Pradesh, IN;

Rohit Jindal, Braintree, MA (US);

Mehdi Ghodbane, Piscataway, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/00 (2006.01); G01N 33/50 (2006.01); G01N 33/543 (2006.01); G01N 33/68 (2006.01); B01L 3/00 (2006.01); C12M 3/06 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5023 (2013.01); B01L 3/502761 (2013.01); G01N 33/5047 (2013.01); G01N 33/5082 (2013.01); G01N 33/54366 (2013.01); G01N 33/6863 (2013.01); B01L 2200/0668 (2013.01); B01L 2300/0877 (2013.01); B01L 2400/086 (2013.01); C12M 23/16 (2013.01); G01N 33/5064 (2013.01); G01N 2333/7051 (2013.01); G01N 2333/70596 (2013.01); G01N 2333/7151 (2013.01); G01N 2333/7155 (2013.01); G01N 2500/10 (2013.01);
Abstract

This invention discloses devices and methods for high throughput skin sensitization detection. The devices comprise a microfabricated chamber comprising a region having one or more input channels and an outlet, and a face suitable for mounting a skin tissue and in fluidic communication with the region. The devices can be used in the methods for determining a prognosis of sensitization in an animal subject and identifying compounds that do not cause sensitization and thus are suitable for preparing cosmetic compositions.


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