The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2019

Filed:

Aug. 07, 2012
Applicants:

Joergen Hansen, Frederiksberg, DK;

Esben Halkjaer Hansen, Frederiksberg, DK;

Honey Polur, Durham, NC (US);

Joseph M. Sheridan, Royston, GB;

Jonathan R. Heal, Attenborough, GB;

William D. O. Hamilton, Royston, GB;

Inventors:

Joergen Hansen, Frederiksberg, DK;

Esben Halkjaer Hansen, Frederiksberg, DK;

Honey Polur, Durham, NC (US);

Joseph M. Sheridan, Royston, GB;

Jonathan R. Heal, Attenborough, GB;

William D. O. Hamilton, Royston, GB;

Assignees:

International Flavors & Fragrances Inc., New York, NY (US);

Evolva SA, Reinach, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/395 (2006.01); C12N 15/52 (2006.01); C12N 15/82 (2006.01); C12N 9/04 (2006.01); C12N 9/10 (2006.01); C12N 9/88 (2006.01); C12P 7/24 (2006.01); C12P 19/46 (2006.01); A23L 33/105 (2016.01);
U.S. Cl.
CPC ...
C12N 9/0006 (2013.01); A23L 33/105 (2016.08); C12N 9/1011 (2013.01); C12N 9/88 (2013.01); C12P 7/24 (2013.01); C12P 19/46 (2013.01); C12Y 201/01006 (2013.01); C12Y 402/01118 (2013.01); C07K 14/395 (2013.01); C12N 15/8221 (2013.01); C12Y 101/01025 (2013.01);
Abstract

Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a mutant AROM polypeptide and/or mutant catechol-O-methyltransferase polypeptide alone or in combination with one or more vanillin biosynthetic enzymes or UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce vanillin or vanillin beta-D-glucoside.


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