The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 19, 2019
Filed:
Jul. 19, 2016
Applicant:
Grifols, S.a., Barcelona, ES;
Inventors:
Brett Buno, Durham, NC (US);
Terri Journigan, Wendell, NC (US);
Joann Hotta, Raleigh, NC (US);
Michael Burdick, Durham, NC (US);
Assignee:
GRIFOLS, S.A., Barcelona, ES;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C12Q 1/70 (2006.01); G01N 33/576 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); C12N 5/0018 (2013.01); C12Q 1/706 (2013.01); C12Q 1/707 (2013.01); G01N 33/576 (2013.01); C12N 2501/05 (2013.01); C12N 2770/28151 (2013.01);
Abstract
Polybrene as an additive in cell culture medium is used in methods for the generation of high-titer hepatitis E virus stocks and assays for titration of hepatitis E virus. A cell culture medium containing polybrene is used for high-titer HEV generation, a method for determining the presence and/or the level of HEV in a sample, and an HEV titration assay using polybrene.