The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2019

Filed:

Dec. 18, 2015
Applicants:

Bergen Teknologioverforing As, Bergen, NO;

Bergenbio Asa, Bergen, NO;

Inventors:

David Robert Micklem, Bergen, NO;

Sergej Kiprijanov, Oslo, NO;

James Bradley Lorens, Bones, NO;

Lavina Ahmed, Bergen, NO;

Linn Hodneland Nilsson, Bergen, NO;

Tone Sandal, Bergen, NO;

Assignees:

BERGEN TEKNOLOGIOVERFORING AS, Bergen, NO;

BERGEBIO ASA, Bergen, NO;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); G01N 33/574 (2006.01); A61K 45/06 (2006.01); C07K 16/30 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); C07K 16/30 (2013.01); C07K 16/3015 (2013.01); C07K 16/3023 (2013.01); C07K 16/3061 (2013.01); G01N 33/574 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/41 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); G01N 2333/71 (2013.01);
Abstract

Described are antibodies that specifically bind to the Axl protein and inhibit the interaction between Axl and the Axl-ligand, Gas6. Also disclosed are methods for the production and use of the anti-Axl antibodies.


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