The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2019

Filed:

Feb. 23, 2016
Applicant:

Ablynx N.v., Zwijnaarde, BE;

Inventors:

Guy Hermans, Merelbeke, BE;

Peter Verheesen, Ghent, BE;

Edward Dolk, Utrecht, NL;

Hendricus Renerus Jacobus Mattheus Hoogenboom, Maastricht, NL;

Michael John Scott Saunders, Brussels, BE;

Hans De Haard, Oudelande, NL;

Renee de Bruin, Amsterdam, NL;

Assignee:

Ablynx N.V., Ghent-Zwijnaarde, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); C07K 14/76 (2006.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
C07K 16/2818 (2013.01); A61K 47/643 (2017.08); C07K 14/76 (2013.01); C07K 16/2803 (2013.01); C07K 16/2827 (2013.01); C07K 2317/22 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/35 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/569 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C07K 2319/31 (2013.01);
Abstract

The present invention relates to amino acid sequences that block the interaction between (a target on) an antigen presenting cell (APC) and (a target on) a T-cell. More particularly, the present invention relates to amino acid sequences that are directed against (as defined herein) a target on an APC (also referred to herein as 'APC target') or a target on a T-cell (also referred to herein as 'T-cell target'). The invention further relates to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences.


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