The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 19, 2019
Filed:
Mar. 15, 2013
Applicant:
Biomet Biologics, Llc, Warsaw, IN (US);
Inventors:
Michael D. Leach, Warsaw, IN (US);
Jennifer E. Woodell-May, Warsaw, IN (US);
Joel C. Higgins, Claypool, IN (US);
Krista O'Shaughnessey, Pierceton, IN (US);
Assignee:
Biomet Manufacturing, LLC, Warsaw, IN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); B01D 11/02 (2006.01); B01D 12/00 (2006.01); B01D 37/00 (2006.01); C07K 14/435 (2006.01); C07K 1/34 (2006.01); A61K 38/17 (2006.01); A61K 38/19 (2006.01); A61K 35/14 (2015.01); A61K 35/28 (2015.01); A61K 35/35 (2015.01); C07K 14/52 (2006.01); A61K 38/20 (2006.01); C07K 14/545 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07K 14/435 (2013.01); A61K 35/14 (2013.01); A61K 35/28 (2013.01); A61K 35/35 (2013.01); A61K 38/1793 (2013.01); A61K 38/1808 (2013.01); A61K 38/1841 (2013.01); A61K 38/1858 (2013.01); A61K 38/1866 (2013.01); A61K 38/191 (2013.01); A61K 38/2006 (2013.01); C07K 1/34 (2013.01); C07K 14/52 (2013.01); C07K 14/545 (2013.01); G01N 33/5002 (2013.01); G01N 33/5005 (2013.01);
Abstract
Non-centrifugal methods for generating a solution rich in interleukin-1 receptor antagonist from a tissue comprising cytokine-producing cells. The solution rich in IL-1ra can also include at least one of sTNF-RI, sTNF-RII, IGF-I, EGF, HGF, PDGF-AB, PDGF-BB, VEGF, TGF-β1, and sIL-1 RII.