The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 19, 2019
Filed:
Sep. 09, 2015
Daiichi Sankyo Company, Limited, Chuo-ku, Tokyo, JP;
Yuji Kasuya, Sumida-ku, JP;
Yasuhiro Nakagami, Kobe, JP;
Emiko Hatano, Urayasu, JP;
Tatsuya Inoue, Ota-ku, JP;
Kazuhiro Yoshida, Setagaya-ku, JP;
Satoshi Komoriya, Fujisawa, JP;
Yoko Murakami, Bunkyo-ku, JP;
Masaru Iwasaki, Edogawa-ku, JP;
Atsunobu Sakamoto, Edogawa-ku, JP;
Kayoko Masuda, Setagaya-ku, JP;
Masako Minami, Taitou-ku, JP;
Mayumi Iizuka, Edogawa-ku, JP;
Yasunori Ono, Ichikawa, JP;
Takashi Ohnuki, Yamato, JP;
Daiichi Sankyo Company, Limited, Chuo-ku, JP;
Abstract
The present invention relates to a terpenoid derivative that has the ability to activate the Keap1/Nrf2/ARE signaling pathway and is excellent in anti-inflammatory action and cytoprotective action, and a sustained-release pharmaceutical composition effective for the treatment and prevention of a posterior eye disease caused by oxidative stress, comprising the terpenoid derivative as an active ingredient. The present invention provides a local administration-type sustained-release pharmaceutical composition for the treatment or prevention of a posterior eye disease, comprising the terpenoid derivative of the present invention as an active ingredient, wherein the sustained-release pharmaceutical composition maintains a pharmacological action thereof for 1 week or longer by the sustained release of the terpenoid derivative under physiological conditions and has a base material administrable to the vitreous body and a form administrable to the vitreous body.